Rationale The goal of this simulation is to calculate power/sample size for a given hazard ratio (HR) in survival analysis by taking advantage of modern multicore computers. When we conduct simulation, generally, we simulate datasets for different combinations of sample size and HR then compute the proportion of rejection given the…

I work in a large pharmaceutical company. Every year we hire many interns. From my experience, we hardly find enough students who truly could fit our projects. On the other hand, students might wonder why I was not hired, although I met all job requirements. One of the reasons is…

I work in a large pharmaceutical company. Every year we hire many interns. From my experience, we hardly find enough students who truly could fit our projects. On the other hand, students might wonder why I was not hired, although I met all job requirements. One of the reasons is…

Rationale The goal of this simulation is to calculate power/sample size for a given hazard ratio (HR) in survival analysis by taking advantage of modern multicore computers. When we conduct simulation, generally, we simulate datasets for different combinations of sample size and HR then compute the proportion of rejection given the…

High throughput data is very common in modern science. The main property of these data is high-dimensionality; that is, the number of features is larger than the number of observations. There are many ways to study this kind of data, and multiple hypothesis testing is one of them. In a…